Citrus BergamotCitrus Bergamot is the latest natural supplement for lowering cholesterol levels and can also lower blood sugar as well. This new food supplement has taken the medical world by storm, even being used in place of statin drugs in some cases.

Truth be known, it’s an interesting compound but has many varied effects. It’s ability to block the synthesis of cholesterol means that it could cause problems in some people who’s cholesterol levels are too low to start with.

It is beneficial in other ways though, so it’s definitely something you need to discuss with an integrative cardiologist, if you are attempting to use it as a means of lowering cholesterol levels.

What is Citrus Bergamot?

Citrus Bergamot is a small sized tree that will blossom during winter. In terms of bitterness, it is less bitter than lemon but more than grapefruit. It is used as an ingredient in Earl Grey Tea. The juice of this plant is not consumed, but is used as a treatment for malaria, and the oil is used for aromatherapy.

A fragrant orange sized yellow green citrus fruit that is grown commercially in the Calabria region of Southern Italy. It is grown also in the southern part of France, as well as the south of Turkey.

The essential oil of Bergamot is a dark greenish-brown in color and is extracted in Cote d’Ivorie. It is grown in Antalya Turkey for use in marmalade.

Unlike other citrus fruits, Bergamot has very large amounts of polyphenols. Two of those compounds Melitidin, and Brutieridin, block the synthesis of cholesterol in the liver in much the same way statin drugs do.

It also has a similar effect to grapefruit in that it can affect the way your body metabolizes various pharmaceutical drugs.

How does it work?

Bergemot reduces the amount of triglycerides and cholesterol you would ordinarily absorb through meals. It also reduces the biosynthesis of cholesterol in the body. It also helps glucose get into cells which is beneficial for diabetics.

It blocks the HMG CoA Reductase Enzyme, which is what statin drugs do. It contains substances called polyphenolic flavanoids that suppress cholesterol production in much the same way that statins do, but it works in a different way that does not seem to deplete coenzyme Q10.

There are three main modes of action:

  • Blocks the HMG CoA Reductase Enzyme
  • Works on insulin receptors to improve shuttling of glucose into cells
  • Blocks cholesterol absorption in the intestine similar to plant sterols

What are some of the benefits of Citrus Bergamot?

  • It promotes fat burning and improves blood sugar control. This helps combat obesity and promotes weight loss.
  • It combats arterial stiffness due to it’s effect on sugar metabolism, and the benefits of the flavinoids it contains.
  • Can reduces LDL and triglycerides and increase HDL cholesterol
  • Helps in lowering blood pressure
  • Bergamot shows anti-tumor action and may be effective in combating neuroblastoma and other metastic cancers
  • It demonstrates anti-inflammatory and antioxidant properties that improve endothelial function

How is Bergamot taken?

When used for it’s cholesterol lowering effect, it would be taken in capsule form at appropriate doses, and this is where things get tricky. The medical profession knows a lot about drugs and the dosages that should be given, but not very much about vitamins, nutraceuticals, and herbs.

Citrus Bergamot capsulesDosage recommendations for this supplement are anecdotal and not the result of carefully controlled trials and years of clinical case studies and experience. Great care should be taken with this supplement, as it does mimic the effects of statin drugs, and thus could have some of the same side effects.

Given this fact, I think it’s wise to seek the advice of a complementary physician, who has knowledge of alternative treatments.

In research conducted at the Scripps Integrated Medicine Conference in San Diego California, in January 2012, they used 1,000 milligrams per day and got an average reduction in total cholesterol levels of 29%, a 36% reduction in LDL, and increase HDL cholesterol by 40%!

Reductions in triglycerides of 30%, and blood glucose of 20% on average were also noted. From this result the researches concluded that Citrus Bergamot extract at a dosage of 1,000 milligrams per day was an effective substitute for statin drugs for lowering LDL cholesterol, and also treating metabolic syndrome.

In Summary:

Citrus Bergamot is an interesting compound with some powerful effects on cholesterol metabolism, blood sugar control, and metabolic syndrome. It has demonstrated anti-tumor effects as well. However due to it’s statin like mode of action, I would very strongly suggest that you use it ONLY under the direction of a doctor who is knowledgeable about alternative medicine.

The doctor can help you determine if it’s right for you, and if so, how to arrive at a safe and effective dosage.

Research references:

Fitoterapia. 2011 Apr;82(3):309-16. doi: 10.1016/j.fitote.2010.10.014. Epub 2010 Nov 4.
Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies.

Fitoterapia. 2010 Sep;81(6):453-61. doi: 10.1016/j.fitote.2010.01.013. Epub 2010 Jan 20.
Neuropharmacology of the essential oil of bergamot.

Int J Cardiol. 2013 Dec 10;170(2):140-5. doi: 10.1016/j.ijcard.2013.08.125. Epub 2013 Sep 8.
Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia.

Fitoterapia. 2014 Jun;95:83-92. doi: 10.1016/j.fitote.2014.02.009. Epub 2014 Mar 2.
Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models.

PLoS One. 2013 Apr 16;8(4):e61484. doi: 10.1371/journal.pone.0061484. Print 2013.
Mechanisms underlying the anti-tumoral effects of Citrus Bergamia juice.

A home cholesterol test is one way that you can begin taking more responsibility for your health, and understanding just how your diet and lifestyle affect your cholesterol values. A cholesterol blood test will determine if you have normal cholesterol levels, and if not, the cholesterol test results can be read and further interpreted by your doctor.

Testing in a home environment is just not as accurate as the tests performed in your doctor’s office. Home test kits are just not engineered to replace a full diagnostic lab, but they don’t have to. These tests are meant to help you keep track of your cholesterol values, and make adjustments to your diet and lifestyle when you need to.

Caution: Never substitute a home cholesterol test, or home testing (of any kind) for proper diagnosis and treatment from your doctor. Your physician can measure cholesterol levels much more precisely using lab tests that you can with a home test, so the lab work your doctor orders on your blood samples is the most accurate and best way to establish what your levels really are.

Home tests help you keep track of markers like cholesterol or blood sugar, but they are not meant to be substitutes for a proper medical test or diagnosis!

You need to be tested by your doctor to establish what is called a “baseline,” and once you know what this is, then home testing can tell you whether your levels are going up or down. These measurements are “relative” and their real value is helping you to track how your cholesterol levels are responding to diet and exercise.

Although the home cholesterol test is fairly accurate, it should be calibrated with the cholesterol blood test that you have in your doctor’s office. Take your home test kit with you and test yourself at the same time your doctor draws your blood for the full laboratory test.

That way you can see how the results of the two tests differ, and will be able to get an idea of just how far off the cholesterol test results are between the cholesterol blood test you get in the doctor’s office and the home cholesterol test.

When you buy online, read reviews carefully, do a little research into the product you are buying. Some of these cholesterol testing systems are expensive (over $100.00) dollars, require you to buy a testing unit, and additional test strips for it. This can run well over $100.00 for both.

Obviously you would not use a home cholesterol test as often as you would use a glucose monitor for instance. You are merely trying to track your normal cholesterol levels, and see how they respond to changes you make in your diet and lifestyle.

Here are some brands:

  •     CholesTrak, Home Access Instant Cholesterol Test
  •     Cardio Check (gives you both HDL and LDL level)
  •     Lifestream Personal Cholesterol Monitor (give you both HDL and LDL)

“Cardio Check” seemed to have by far the highest customer satisfaction ratings online.

A home cholesterol test should can run between $10.00 and $150.00 depending on how comprehensive the test is. Some tests only give you total cholesterol, which is not a very useful indicator. It may tell you how your total cholesterol levels is responding to diet or exercise, but it does not indicate real risk factors.

For that you need to know your HDL level, and a test that gives you both LDL and HDL levels will give you the information to assess risk factors more clearly. When you know both your LDL and HDL levels, you can calculate total cholesterol, as well as HDL/LDL ratio which is the best cholesterol values which indicate your heart disease risk.

The home cholesterol test to look for is one that at least gives you both HDL and LDL levels. These should run you about $30-$50 and are available online. Again you will have to check it for accuracy against the cholesterol blood test from your doctor, but if it gives you a somewhat reliable indicator of your cholesterol values, then it’s doing it’s job.