vitamin-d-sourcesFew people are aware of the relationship between vitamin d and cholesterol, but it’s an important one and it shouldn’t be ignored. Although it’s called a vitamin, it’s actually a hormone and a deficiency of it can be life threatening!

It’s Actually a Hormone

Vitamin d refers to a number of is a fat soluble steroid molecules that are involved in the absorption of important minerals in your intestinal tract.

The two most important factors are:
vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol)

It’s also called the “sunshine vitamin” because it can be bio synthesized in your body when your skin is exposed to natural sunlight. This is especially important to people of African ancestry that live in temperate climates that have long winters.

Since their darker skin pigmentation filters out some of the suns rays, they are at increased risk of deficiency because of their skin filtering out natural sunlight (especially during long winters.)

For black people, supplements are a MUST! It appears that pretty much every disease that people of African descent suffer from disproportionately is linked with vitamin d deficiency. This is not widely known, but can still cause lots of health problems that could be avoided with wise use of supplementation.

The Cholesterol Connection

The human body is amazingly resourceful at bio synthesizing what it needs from what we put into our bodies. Thus when we have a deficiency of vitamin d the body will make it from cholesterol. This can cause your cholesterol levels to rise, because your body needs the extra cholesterol in order to synthesize this vitamin/hormone.

You have read in this blog that lowering cholesterol is not necessarily needed to prevent heart disease because it has been found not to be a direct causative factor. However if your cholesterol levels are elevated because of a lack of vitamin d then you need to take steps to supply your body with this nutrient by getting more sun exposure and taking supplements when you can’t get enough sun, such as in the winter.

Elevated cholesterol levels can indicate other problems in your body that you need to address. This is another reason why statin use can be problematic. It can mask the symptom (elevated cholesterol) that is being caused by another problem (like vitamin d deficiency).

Effects of Vitamin D Deficiency

  • increased risk of heart attack and stroke
  • depression
  • Parkinson’s Disease
  • increased risk of cancer
  • increased risk of infection
  • increased risk of multiple sclerosis

Some Food Sources of Vitamin D

  • Cod liver oil
  • Butter from grass fed cows
  • Beef or Calves liver
  • Egg yolks
  • Cheese
  • Water packed tuna
  • Oil packed sardines

Supplementing Vitamin D

Supplementary forms of this vitamin can be found in any health food store. My favorite is Jarrow Formulas D3. I opt for 5,000 units per day in the winter and half that dosage in the summer. It is difficult to overdose on this vitamin, as long as you are not using a synthetic version of it.

The ideal situation is that you get your levels tested by a doctor and do follow ups until the levels are where they are supposed to be. This is a fat soluble vitamin and so should be taken with a meal that contains healthy fats.

Vitamin k2 should be taken with vitamin d as those two nutrients work togegher to ewnsure that your body handles calcium properly. One of the top experts on vitamin K2 Dr. Rheaume Bleue suggests a ratio of 100-200 micrograms of K2 for every 1,000 IUs of vitamin d.   Again I would go with Jarrow Formulas MK-7, combined with their D3 product.

Sun Expose is Healthy

It’s been said before, but bears repeating…sun exposure is HEALTHY! Human beings evolved on the surface of the Earth. We NEED sun exposure in order for out bodies to function properly. Don’t avoid getting sunlight, because if you do, you are undermining your health in a critical way.

sunshine vitamin

sunshine helps your body synthesize vitamin D

Use common sense of course. Don’t overdo it, as too much of anything can be a problem, but remember that getting out in the sun and fresh air has benefits that go far beyond making you feel good and improving your mood.

How Much Sun Exposure?

This depends on how dark your skin is. Light skinned people should avoid prolonged exposure such as beyond 10-15 minutes in the sun. Darker skinned people of course can tolerate longer exposure, but you should be conservative with your time in the sun and gradually build a tolerance to sun exposure over time as you get more tanned.

Wearing a wide brim hat, proper sunglasses, and long sleeve clothing can help protect you as well. Remember also that you can get burned even on a hazy day because enough of the suns rays still get through and you may not be aware of how long you have been exposed.

Remember also that sunblock will prevent your body from making the vitamin d it needs from sun exposure, so If you are using sun screens on your skin you are defeating the purpose of getting sunlight.

artichoke-leaf-extract

Artichoke leaf extract capsules

Did you know that better heart health and lower cardiovascular risk can be had with two natural products that you can buy right over the counter? Well it’s true! Artichoke extract and pantethine are what we are talking about, and it can help you cut your risk of heart disease without dangerous side effects.

Interested? Well then read on…

Millions of people use the popular statin drugs to lower cholesterol but heart disease still continues to be the number one killer of Americans. Statins lower LDL cholesterol and inflammation while raising hdl but they have serious side effects that can dramatically lower the quality of life and put you at risk for serious health complications. One area where statins fall short is raising HDL levels. They don’t elevate HDL enough to significantly improve your HDL LDL ratio.

Statins can also raise your risk for rhabdomyolysis: (muscle breakdown), kidney damage, and even diabetes. This is due to it’s interference in the biochemical pathways which bio-synthesize both cholesterol and coenzyme Q10, which your body needs to help create energy from the foods you eat in order to power the cells of the heart.

Thus statins not only commonly cause muscle pain and weakness, but can also ironically increase the risk for cardiomyopathy which is muscle damage to the heart!

While there are certain people for whom the risk of statins is justified by their effectiveness, the vast majority of people would likely be better off with natural alternatives, and there are two good ones we have access to, pantethine and artichoke extract. These two supplements or “nutraceuticals” as they are sometimes called, can lower LDL AND raise HDL safely and naturally without the risks of serious side effects.

Enter Artichoke Extract…

An extract from artichoke leaves can raise your levels of HDL, while pantethine which is an analog of vitamin b-5 can lower LDL without causing deficiency of coenzyme q10 (as statins do). The use of these two compounds together has been shown to reduce by up to 11% the risk of heart disease. Pretty powerful stuff for two natural substances!

Artichokes which are actually considered to be in the “thistle’ family contain powerful substances called flavonoids that can lower LDL levels and increase HDL. The flavonoids act as antioxidants, preventing the oxidation of LDL particles in your arteries. In addition artichoke extract can increase your levels of bile acids, which help remove cholesterol from the body.

The clinical results with artichoke extract were based upon an intake of 1,800 mg/day of dry artichoke leaf extract for 6 weeks. This resulted in an 18.5% reduction in total cholesterol, with an improvement in the HDL/LDL ratio. It was also shown to cause an average of over 36% increase in endothelial function (the layer of cells that line the arteries) which also helps to prevent heart disease.

Next Up – Pantethine…

Pantethine lowers LDL levels without reducing coenzyme q10. It does this by inceasing the breakdown rate of serum cholesterol and reducing the rate of cholesterol synthesis. Pantethineis an energy molecule that helps increase fat burning in the body.

It also improves the ratio of HDL to total cholesterol which has a protective effect on your artery walls, reducing plaque formation and lesions in the aorta and coronary arteries.

A four month study was undertaken where the dosage of pantethine was 600mg/day for the first eight weeks and then a higher dose of 900 mg/day for the second eight weeks. This resulted in a modest decrease of LDL with a slight increase in coenzyme q10, unlike statin drugs.

When you consider that every reduction of 1% in LDL levels equals a 1% reduction in heart disease risk, pantethine significantly reduces the risk of heart attack by 11%. This is a very significant result and more reason to include pantethine in your supplement regimen.

In Summary…

All of us are at risk for heart disease as we age, and the primary issue in that risk is elevations in inflammatory LDL particles and low HDL levels. Many of the
patients put on statin drugs stop taking them because of the severity of the side effects, leaving them vulnerable to risk of heart disease once more. However the
combination of pantethine and artichoke extract can help lower LDL and raise protective HDL without the side effects that characterize statin use.

People who are at low risk may be able to achieve effective protection just by using these natural compounds rather than statins drugs. For people who have
extremely high LDL and/or very low HDL, a combination of low dose statins AND natural compounds like pantethine and artichoke extract may be the ideal
combination to avoid side effects AND effectively decrease the risk of heart disease.

As always, any therapy whether drug based OR natural that is intended to protect against heart disease should be managed by your doctor, possibly with the help of
a nutritionist or other wellness professional who is well versed in natural healing therapies, nutrients, and nutraceuticals.

Medical References:

Atherosclerosis. 1984 Jan;50(1):73-83.
Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia.
Gaddi A, Descovich GC, Noseda G, Fragiacomo C, Colombo L, Craveri A, Montanari G, Sirtori CR.

Plant Foods Hum Nutr. 2015 Aug 27. [Epub ahead of print]
Pharmacological Studies of Artichoke Leaf Extract and Their Health Benefits.
Salem MB1, Affes H, Ksouda K, Dhouibi R, Sahnoun Z, Hammami S, Zeghal KM.
Int J Food Sci Nutr. 2013 Feb;64(1):7-15. doi: 10.3109/09637486.2012.700920. Epub 2012 Jun 29.
Beneficial effects of artichoke leaf extract supplementation on increasing HDL-cholesterol in subjects with primary mild hypercholesterolaemia: a double-blind, randomized, placebo-controlled trial.
Rondanelli M1, Giacosa A, Opizzi A, Faliva MA, Sala P, Perna S, Riva A, Morazzoni P, Bombardelli E.

New cholesterol guidelines are being driven by drug company profits and promoted through the concept of “family history” or familial hypercholesterolemia! But what is the truth about heart disease and the alledged protective effect of statins?

Do these drugs protect aginst heart attacks and extend lifespans or is tghe truth about their effectiness compromised by faulty scientific studies paid for by the same companies that want to market these drugs as life savers?

This analysis by Drt. David Newman sheds light on the problems with studies called “meta-analysis” and how the results of these studies may mislead even doctors as to the safety and effectivenss of statin drugs for their cardiac patients.

The Diet-Heart Myth: Statins Don’t Save Lives in People …

http://chriskresser.com/ Mon, 13 May 2013 08:00:00 -0700

An analysis by Dr. David Newman in 2010 which drew on large meta-analyses of statins found that among those with pre-existing heart disease that took statins for 5 years (1): ….. Certainly I have a few older female patients who had chronic high LDL and LDL-P with family history even, but no other risk factors I could see, where I tested them up and down for evidence of vascular disease (they were concerned with being a walking time bomb) and found NONE – no …

Read more …

cholesterol-particlesHow did we arrive at the conclusion that LDL cholesterol is the villain in heart disease?

Well…once again we see the mistakes made by researchers that lead us to think of LDL as the culprit.

A little history…

It had to do with a machine used in the laboratory, called an analytical centrifuge that created evidence that ultimately mislead researchers and clouded the issue of cholesterol sub-particles.

Invented in 1949 and used until 2004, this device was used to spin blood plasma samples at 40,000 rpm to separate out the cholesterol fractions such as HDL and LDL.

However this spinning process cannot separate the particles with the precision required to identify all of the sub-fractions of cholesterol that are present in the blood. It may have been state of the art when it was first used, but still fell far short in the accuracy required to actually identify all the sub-fractions of cholesterol.

This started the characterization of cholesterol particles as either good or bad cholesterol, depending on the particle density. This was a gross oversimplification that stuck in the minds of the public.

For many years this simplified version of a person’s risk of heart disease based on their ratio of good and bad cholesterol stood as the cutting edge of cholesterol testing and heart disease prevention.

This was accompanied by the now debunked view that saturated fats caused heart disease because of their association with cholesterol. People avoided saturated fats out of a fear that was not founded in good science.

They also consumed statins, the most prescribed class of drugs on Earth due to the same fear of cholesterol and it’s supposed relationship to heart attacks.

Americans have consumed some 14 billion dollars in cholesterol lowering drugs, which some health experts have advocated be given to people of all ages including children allegedly to prevent heart disease.

John Abramson argues in his book Overdosed America that lowering LDL cholesterol has inadvertently become the main focus of preventative medical care in the United States.

Cutting edge thinking about LDL cholesterol

Yet a more recent breakthrough utilizing a new technology called ion mobility analysis has shaken the traditional concept of cholesterol’s role in heart disease to the core, and called the entire LDL cholesterol theory into question.

Ronald M. Krauss, of the Children’s Hospital Oakland Research Institute, is using ion mobility analysis to count cholesterol particles such as LDL and HDL down to the smallest sub particle types using principles of physics.

Even though it’s extremely expensive and not widely available, this technology has helped to rewrite the rules on how we think about cholesterol and heart disease.

Rather than continuing to believe that LDL cholesterol is the bad cholesterol here, we now know that there are four types of LDL particles that factor into the risk of heart disease.

Some LDL particles are benign and others more dangerous. Thus it makes no sense to continue to base diet and drug recommendations on an outdated theory when the science regarding cholesterol particle types is far more precise now.

We could be using drugs that target the wrong particles, and making dietary recommendations that are doing more harm than good at this point, all while dramatically escalating health care costs and actually making treatment less effective!

Low Density Lipoproteins

LDL comes in four sizes:

  • Large (big fluffy particles)
  • Medium
  • Small
  • Very Small

As the LDL particle size decreases the particles become more dense, (and more dangerous). This is because the large fluffy particles can’t lodge in your artery walls as plaque, while smaller dense LDLs CAN!

High fat diets tend to increase the large fluffy LDL particles, while low-fat high carbohydrate diets increase the smaller more dense particles.

From this you can see why the standard medical advice about how we should eat to avoid heart disease is seriously flawed! It was all based on an oversimplified and outmoded concept of the nature of cholesterol particles.

Typical cholesterol tests can’t differentiate between large and small LDL particles. There are also genetic, environmental, and lifestyle factors that affect LDL particle size.

Enter “Ion Mobility Analysis”

Using ion mobility analysis, Dr. Krauss and his colleagues determined that there are some 11 different particles. This was done using a sample of 4,600 healthy men and women volunteers.

Eight percent of the test subjects went on to develop heart disease, and using statistical algorithms the researchers developed a series of three very accurate predictors for who would go on to develop heart disease.

Here are the correlations that Dr. Kraus’s team found:

    1. High levels of small and medium LDL particles with low HDL (called atherogenic lipoprotein phenotype) Also known as pattern B
    2. Low HDL levels
    3. High total LDL cholesterol

So as it turns out LDL cholesterol and the risk of heart disease is a complex relationship that standard cholesterol tests are almost useless to predict.

The PLAC Test

There is one test however that can give you a better idea of what your risk is. You can read about it in my article called “The PLAC Test.” This is the latest test that really utilizes our new knowledge of LDL to make more accurate predictions about what your real risk for heart disease is.

Using this test you can make better choices about lifestyle and diet, because they are based upon a more complete understanding of the science of cholesterol particles.

Citrus BergamotCitrus Bergamot is the latest natural supplement for lowering cholesterol levels and can also lower blood sugar as well. This new food supplement has taken the medical world by storm, even being used in place of statin drugs in some cases.

Truth be known, it’s an interesting compound but has many varied effects. It’s ability to block the synthesis of cholesterol means that it could cause problems in some people who’s cholesterol levels are too low to start with.

It is beneficial in other ways though, so it’s definitely something you need to discuss with an integrative cardiologist, if you are attempting to use it as a means of lowering cholesterol levels.

What is Citrus Bergamot?

Citrus Bergamot is a small sized tree that will blossom during winter. In terms of bitterness, it is less bitter than lemon but more than grapefruit. It is used as an ingredient in Earl Grey Tea. The juice of this plant is not consumed, but is used as a treatment for malaria, and the oil is used for aromatherapy.

A fragrant orange sized yellow green citrus fruit that is grown commercially in the Calabria region of Southern Italy. It is grown also in the southern part of France, as well as the south of Turkey.

The essential oil of Bergamot is a dark greenish-brown in color and is extracted in Cote d’Ivorie. It is grown in Antalya Turkey for use in marmalade.

Unlike other citrus fruits, Bergamot has very large amounts of polyphenols. Two of those compounds Melitidin, and Brutieridin, block the synthesis of cholesterol in the liver in much the same way statin drugs do.

It also has a similar effect to grapefruit in that it can affect the way your body metabolizes various pharmaceutical drugs.

How does it work?

Bergemot reduces the amount of triglycerides and cholesterol you would ordinarily absorb through meals. It also reduces the biosynthesis of cholesterol in the body. It also helps glucose get into cells which is beneficial for diabetics.

It blocks the HMG CoA Reductase Enzyme, which is what statin drugs do. It contains substances called polyphenolic flavanoids that suppress cholesterol production in much the same way that statins do, but it works in a different way that does not seem to deplete coenzyme Q10.

There are three main modes of action:

  • Blocks the HMG CoA Reductase Enzyme
  • Works on insulin receptors to improve shuttling of glucose into cells
  • Blocks cholesterol absorption in the intestine similar to plant sterols

What are some of the benefits of Citrus Bergamot?

  • It promotes fat burning and improves blood sugar control. This helps combat obesity and promotes weight loss.
  • It combats arterial stiffness due to it’s effect on sugar metabolism, and the benefits of the flavinoids it contains.
  • Can reduces LDL and triglycerides and increase HDL cholesterol
  • Helps in lowering blood pressure
  • Bergamot shows anti-tumor action and may be effective in combating neuroblastoma and other metastic cancers
  • It demonstrates anti-inflammatory and antioxidant properties that improve endothelial function

How is Bergamot taken?

When used for it’s cholesterol lowering effect, it would be taken in capsule form at appropriate doses, and this is where things get tricky. The medical profession knows a lot about drugs and the dosages that should be given, but not very much about vitamins, nutraceuticals, and herbs.

Citrus Bergamot capsulesDosage recommendations for this supplement are anecdotal and not the result of carefully controlled trials and years of clinical case studies and experience. Great care should be taken with this supplement, as it does mimic the effects of statin drugs, and thus could have some of the same side effects.

Given this fact, I think it’s wise to seek the advice of a complementary physician, who has knowledge of alternative treatments.

In research conducted at the Scripps Integrated Medicine Conference in San Diego California, in January 2012, they used 1,000 milligrams per day and got an average reduction in total cholesterol levels of 29%, a 36% reduction in LDL, and increase HDL cholesterol by 40%!

Reductions in triglycerides of 30%, and blood glucose of 20% on average were also noted. From this result the researches concluded that Citrus Bergamot extract at a dosage of 1,000 milligrams per day was an effective substitute for statin drugs for lowering LDL cholesterol, and also treating metabolic syndrome.

In Summary:

Citrus Bergamot is an interesting compound with some powerful effects on cholesterol metabolism, blood sugar control, and metabolic syndrome. It has demonstrated anti-tumor effects as well. However due to it’s statin like mode of action, I would very strongly suggest that you use it ONLY under the direction of a doctor who is knowledgeable about alternative medicine.

The doctor can help you determine if it’s right for you, and if so, how to arrive at a safe and effective dosage.

Research references:

Fitoterapia. 2011 Apr;82(3):309-16. doi: 10.1016/j.fitote.2010.10.014. Epub 2010 Nov 4.
Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies.

Fitoterapia. 2010 Sep;81(6):453-61. doi: 10.1016/j.fitote.2010.01.013. Epub 2010 Jan 20.
Neuropharmacology of the essential oil of bergamot.

Int J Cardiol. 2013 Dec 10;170(2):140-5. doi: 10.1016/j.ijcard.2013.08.125. Epub 2013 Sep 8.
Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia.

Fitoterapia. 2014 Jun;95:83-92. doi: 10.1016/j.fitote.2014.02.009. Epub 2014 Mar 2.
Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models.

PLoS One. 2013 Apr 16;8(4):e61484. doi: 10.1371/journal.pone.0061484. Print 2013.
Mechanisms underlying the anti-tumoral effects of Citrus Bergamia juice.

soy lecithing granules

Lecithin as a food to lower cholesterol is another natural strategy to improve your lipid (fat) profile without the use of toxic drugs, such as statins.

Lecithin is a compound found in soybeans, eggs,  sunflower, and other sources, which has the ability to help lower cholesterol levels.

Remember that when we talk about lowering cholesterol, we are really referring to optimizing your cholesterol levels. Cholesterol is often elevated by other things going on in the body. Things like insulin resistance, vitamin-d deficiency, and stress can all raise cholesterol levels.

When levels are high often this indicates that there are problems with the body that can be serious if they are not taken care of. High cholesterol levels are like the “canary in the coal mine” so to speak. If they are elevated we need to make sure we know why, and correct it.

Lecithin (also called phosphatidylcholine) is a “phospholipid compound” that supplies the b-vitamin choline, which is vital to the health of your brain and nervous system. This natural compound (lecithin) can help promote healthy cholesterol levels, but there are some things you need to know before you add it to your diet!

As a food to lower cholesterol, soy lecithin (from soybeans) may not be the best way to go, as soy contains phyto-estrogens and can cause a number of problems especially for men.  Sunflower lecithin on the other hand does not pose those problems and so would be a much better way to go, if you are using it to improve your cholesterol profile.

The following foods are sources of lecithin:

  • Animal sources:  eggs, meat, dairy
  • Vegan sources:   nuts, seeds, soy, sunflower

Eggs contain the highest amounts for any animal based food, and if you are a vegetarian, you would likely have to supplement with lecithin granules, preferably made from sunflower plants, instead of soybeans.

These lecithin granules have a pleasant nutty flavor and can be added to either liquid or solid food depending on your taste and preferences. They are one of the few things that are good for you that actually taste good!

This food does act as an emulsifier (mixes water and oil) and can be used in blending protein drinks or vegetable smoothies such as you might make in the Nutribullet! Dr. Peter D’Adamo has a recipe for something he calls the “Membrane Fluidizer Cocktail,” or “Membrosia Cocktail.”

The recipe goes something like this:

Use guava, grapefruit, or watermelon juice as a base
add 1/2 to 1 tablespoon of high-quality flaxseed oil
plus 1 tablespoon of good-quality lecithin granules
shake well until the consistency is uniform
and..enjoy!

Buying and storing lecithin

Make sure that the lecithin granules that you buy in the store are kept under refrigeration, because they oxidize (turn rancid) very easily when they are exposed to light or heat. Always check the expiration dates and pick the freshest bottle. When you get home store your lecithin in the refrigerator at all times!

Lecithin to lower cholesterol……does it work?

I have been unable to find any evidence that lecithin acts as an emulsifier and “flushes” the cholesterol out of your arteries as some people claim. It just doesn’t appear to work in this way. However choline is necessary for optimal health and promoting healthy cholesterol levels.

As a food to lower cholesterol, lecithin provides your body with a good source of choline and for this reason it likely has a positive effect on cholesterol levels. The benefits of lecithin from food sources and supplementation is really enhancing the function of your brain and nervous system.

Since the nervous system is involved in regulating cholesterol metabolism, any thing you do to make it function better will result in an improvement in your cholesterol profile.

Supplementary lecithin comes in either granules or gel caps, which are rather large and may be hard to swallow. When I use lecithin I prefer the granules, and I try to use sunflower lecithin rather than soy lecithin for the reasons I mentioned above.

Do not put lecithin into anything hot, as heat degrades lecithin (it’s poly unsaturated). Follow the dosage recommendations on the label. Since lecithin is a concentrated source of choline, you don’t need a lot.

Remember that lecithin, as a food to lower cholesterol does work but not for the reasons you have likely been told. It provides choline to your body which is essential to the health of your nervous system and thus your body’s ability to maintain healthy cholesterol levels.

medical references:

J Nutr. 1990 Jul;120(7):659-67.
Evidence that polyunsaturated lecithin induces a reduction in plasma cholesterol
level and favorable changes in lipoprotein composition in hypercholesterolemic
rats.
Jimenez MA1, Scarino ML, Vignolini F, Mengheri E.

J Am Diet Assoc. 2003 May;103(5):577-81.
Fat-free foods supplemented with soy stanol-lecithin powder reduce cholesterol
absorption and LDL cholesterol.
Spilburg CA1, Goldberg AC, McGill JB, Stenson WF, Racette SB, Bateman J,
McPherson TB, Ostlund RE Jr.

Atherosclerosis. 1998 Sep;140(1):147-53.
Soy lecithin reduces plasma lipoprotein cholesterol and early atherogenesis in
hypercholesterolemic monkeys and hamsters: beyond linoleate.
Wilson TA1, Meservey CM, Nicolosi RJ.

Natural hormone therapy for optimizing cholesterol has not yet gone mainstream in medicine, but it is going to be a popular new therapy in years to come. Bioidentical hormone therapy is a very safe and natural approach that will help people optimize cholesterol naturally and protect themselves from heart disease as they get older.

As you age, your hormonal systems begins to weaken, and that means that the amounts of critical hormones like, testosterone, DHEA, TSH, estrogen, and progesterone begin to decline. Since all of these hormones need to be in balance for your body to function properly, things begin to go wrong when one or more of these hormones decline, because then that delicate balance can no longer be maintained.

Medical science has slow to embrace natural hormone therapy for optimizing cholesterol , because this idea was considered radical due to misunderstanding by the scientific community. Recent studies have shown a strong correlation between declining hormones and higher cholesterol levels.

Clearly there is a link, and it appears as though restoring hormones to more youthful levels can normalize cholesterol quite effectively. This is logical because when you were younger and your hormone system was stronger and putting out higher levels of these critical hormones, your cholesterol levels were probably lower.

As you aged and your hormone system put out less and less of these hormones, your body was unable to maintain the healthier cholesterol profile your youth. It only makes sense that if you could go back to a more youthful hormone profile, you could significantly lower your risk of heart disease, and probably many other chronic diseases as well.

With that said, lets take a brief look at some research on natural hormone therapy for lowering cholesterol.

Why do declining hormones trigger increases in cholesterol levels?

The body uses cholesterol to make steroid hormones, and the theory is that when the levels of these hormones drop with age, the body tries to provide more cholesterol to the endocrine (hormonal) system to make hormones with.

To confirm this hypothesis, doctors Arnold Smith and Sergey Dzugan conducted a clinical research study on 41 patients with high cholesterol from 1997 to 2003. The results astounded them! In the study they replaced the hormones these patients were lacking, and all subjects experienced a significant drop in their blood cholesterol levels.

When using natural hormone therapy for optimizing cholesterol, it appeared that when normal hormone levels were restored, their bodies “down-regulated” (lowered output) of cholesterol from the liver. This suggests there is a mechanism whereby the body thinks the lower hormone levels are due to a lack of cholesterol, and so it increases it’s cholesterol production to give the body the “precursors” (necessary chemicals) to create these critical hormones.

Furthermore by lowering cholesterol “too much” we you could very well be preventing your body from synthesizing it’s critical hormones by limiting the cholesterol it needs to do it’s job. Nobody ever thinks about the fact that cholesterol is a vital and necessary substance, and that the only way you should go about trying to optimize it is by a natural process, not synthetic drugs.

Natural hormone therapy for lowering cholesterol is the correct approach because it takes into consideration how the body functions, and works with the body’s natural processes to lower cholesterol naturally.

The type of natural hormone therapy that I am speaking of is called bioidentical hormone therapy. It consists of a doctor doing blood and saliva testing on the patient to determine that baseline levels of all of the critical hormones, and then creating a prescription for the necessary hormones to be corrected. This is the principle behind natural hormone therapy.

This prescription is then processed by a compounding pharmacy using plant based hormones that are identical on the molecular level to what your own body produces. The dosages of these hormones the doctor prescribes are very precise and designed to get your critical hormone levels into the middle to high normal range.

This ensures that you only use just enough to create optimal health, and that any possible side effects are minimized or eliminated.

Natural hormone therapy for lowering cholesterol is one of the most effective and natural methods for lowering high cholesterol. It is backed by good scientific research and works WITH your body to safely lower cholesterol levels, rather than interfere with your body’s natural functions as statin drugs do.

References:

Med Hypotheses. 2002 Dec;59(6):751-6.
Hypercholesterolemia treatment: a new hypothesis or just an accident?
Dzugan SA, Arnold Smith R.
Source – North Central Mississippi Regional Cancer Center, Greenwood, Mississippi 38935-0549, USA. sdzugan@tecinfo.com

Ann Agric Environ Med. 2014 Mar 31;21(1):156-60.
Effects of growth hormone and testosterone therapy on aerobic and anaerobic fitness , body composition and lipoprotein profile in middle-aged men.
Zając A1, Wilk M2, Socha T3, Maszczyk A4, Chycki J2.

pantothenic acid capsulesPantothenic acid benefits are not well known to most people but they have important effects on your cardiovascular health. D-calcium pantothenate is helpful in raising HDL cholesterol level, which helps lower your risk of heart disease.

Since the cutting edge in modern medicine involves the use of targeted nutritional supplements to fight disease rather than defaulting to drugs as a first resort, we need to become familiar with some key nutrients and learn how they can help protect against heart disease!

What is pantothenic acid?

D-calcium pantothenate or pantothenic acid is a water soluble b-vitamin (vitamin-b5). It is a very important nutrient and is a precursor to coenzyme A. Coenzyme A is utilized in the metabolism of carbohydrates, and the synthesis of fatty acids, and steroid hormones.

Deficiency of this vitamin in human beings is rare and usually only occurs in bad cases of malnutrition. Symptoms of deficiency include numbness and tingling in the hands and feet, fatigue, headaches, and insomnia.

Pantothenic acid benefits

There are a number of well documented health benefits associated with d-calcium pantothenate such as:

  • Raises HDL cholesterol level
  • Improves skin tone
  • Accelerates healing
  • Protects against lipid peroxidation
  • Increases energy levels
  • Accelerates post surgery healing
  • Helps healing after burn injuries
  • Enhances epithelial function

The most important of the pantothenic acid benefits is it’s ability to raise HDL levels. This is what most directly affects your risk of heart disease. Pantethine is the active form of vitamin B5. Clinical research studies show that pantethine can reduce triglycerides and cholesterol levels and increase HDL levels at the same time.

Food sources of d-calcium pantothenate

Pantothenic acid can be found in common foods and also taken in supplement form. You can get it in the following foods:

  • Meats
  • Whole grains
  • Egg yolks
  • Vegetables like broccoli and avocado
  • Rice
  • Cold water fish

Pantothenic acid benefits can also come from supplements of d-calcium panothenate taken in dosages of 50-100 mg per day. There is no known toxicity threshold for this nutrient and dosages of several grams per day have been reported as having beneficial effects with no signs of toxicity.

Since few doctors are familiar with nutritional supplements and how they should be used, your doctor will probably not be receptive to the idea or know just how these nutrients should be incorporated into your diet.

You should seek the advice of a doctor who practices complementary and integrative medicine, as the best person to advise you in this area. These doctors combine traditional treatments with nutrition and holistic therapies, to get the best results of both approaches.

The best approach is to calibrate the dosage with how you feel and what your objectives are. Raising HDL cholesterol is the most notable of d-calcium pantothenate effects, and you should adjust your dosage to optimize your HDL levels. You may want to have your HDL cholesterol checked to provide a baseline to compare against. This way you will know if it is working.

Pantothenic acid benefits are that this powerful nutrient can help optimize your cholesterol profile and significantly lower your risk of heart disease. It is non toxic and vital to energy production. When you add this vitamin to your nutritional regimen you will significantly improve the quality of your life.

niacin taken to lower cholesterolNiacin for cholesterol has for years been the choice of natural supplements that lower cholesterol.  Niacin (vitamin b-3) can improve cholesterol profiles when used in high doses such as 1,000 to 3,000 milligrams per day.

The use of niacin to lower cholesterol has a lot of sound scientific research behind it. It is considered to be the most effective way to lower cholesterol naturally that is currently available.

This is far above the MRD (minimum daily requirement for vitamin b-3, so when it’s being used to lower cholesterol levels, we call that a “therapeutic dose.” These dosages will cause a reaction call a “niacin flush,” which if you are not used to it may be a little disturbing.

This flushing can be controlled by gradual increases in the dosage so that the body has time to adjust and does not react as strongly.

When using niacin for cholesterol, your skin will turn red and you will feel itchy. This is due to what’s called vasodilation. Niacin (also referred to as nicotinic acid) will lower cholesterol levels, reduce triglycerides, and improve the cholesterol hdl ratio, by boosting hdl levels.

Recent studies have shown that a lower dose (1.5 grams/day) of niacin is effective in lowering ldl levels and also boosting hdl levels. This dosage is better tolerated by the majority of people and is thought to be relatively safe for the liver.

Non-flush – niacin for cholesterol

There is a form of niacin that will not trigger as much flushing as regular niacin. The information on this form is contradictory, but some research indicates that it can be effective at both lowering ldl and raising hdl. It’s called extended release niacin.

People DO still get some flushing from this form, but much less. The issue of people not taking the regular form of niacin to lower cholesterol is because of the unpleasant flush, is not a problem with extended release niacin. Because it is so much milder, it may be more effective simply because people will not avoid taking it. This is called “patient compliance” in medical terms.

Together with using extended release niacin, other strategies to lessen the flush reaction are taking it with meals or snacks, and avoiding alcohol when taking it.

Niacin to lower cholesterol – dosage and side effects

Taking niacin for cholesterol, inhibits the breakdown of hdl in the body, which obviously results in higher hdl levels and a better cholesterol hdl ratio. Higher hdl levels alone lower the risk of heart disease, but niacin helps in another way, by lowering ldl levels as well.

Niacin taken at (1-3 grams/day) prevent the breakdown of fats which the liver uses to make lipoproteins. This lowers levels of both ldl and triglycerides, a very beneficial result. Lower triglyceride levels result in lower levels of ldl cholesterol which also lowers risk of heart attacks.

Side effects beyond the flushing reaction are rare but can include alterations in blood pressure, gastrointestinal distress, and liver damage. Although vitamins that lower cholesterol are safer than drugs, you really should seek expert medical advice when using niacin for cholesterol, both from the standpoint of safety and effectiveness.

You also need medical advice to avoid potential bad reactions from taking niacin for cholesterol with any drugs that you are on. Again the advice of a doctor is needed, because they are familiar with side effects and adverse reactions from combining drugs and nutrients.

Natural supplement or prescription

Odd as it might seem there ARE prescription forms of niacin. I have no information which suggests they work any better than what you can get over the counter, and in fact, they may have more side effects depending on how they were formulated.

If you are advised to take a prescription form of niacin for cholesterol, research the side effects very carefully as they are likely to be greater than what you would get with a natural supplement. You want to lower cholesterol naturally and safely!

Remember also that as effective as niacin is, you have to do all of the other things which protect you from heart disease, like eating a healthy diet, getting the right exercise, and reducing your stress. These strategies work together to keep your heart healthy.