Citrus BergamotCitrus Bergamot is the latest natural supplement for lowering cholesterol levels and can also lower blood sugar as well. This new food supplement has taken the medical world by storm, even being used in place of statin drugs in some cases.

Truth be known, it’s an interesting compound but has many varied effects. It’s ability to block the synthesis of cholesterol means that it could cause problems in some people who’s cholesterol levels are too low to start with.

It is beneficial in other ways though, so it’s definitely something you need to discuss with an integrative cardiologist, if you are attempting to use it as a means of lowering cholesterol levels.

What is Citrus Bergamot?

Citrus Bergamot is a small sized tree that will blossom during winter. In terms of bitterness, it is less bitter than lemon but more than grapefruit. It is used as an ingredient in Earl Grey Tea. The juice of this plant is not consumed, but is used as a treatment for malaria, and the oil is used for aromatherapy.

A fragrant orange sized yellow green citrus fruit that is grown commercially in the Calabria region of Southern Italy. It is grown also in the southern part of France, as well as the south of Turkey.

The essential oil of Bergamot is a dark greenish-brown in color and is extracted in Cote d’Ivorie. It is grown in Antalya Turkey for use in marmalade.

Unlike other citrus fruits, Bergamot has very large amounts of polyphenols. Two of those compounds Melitidin, and Brutieridin, block the synthesis of cholesterol in the liver in much the same way statin drugs do.

It also has a similar effect to grapefruit in that it can affect the way your body metabolizes various pharmaceutical drugs.

How does it work?

Bergemot reduces the amount of triglycerides and cholesterol you would ordinarily absorb through meals. It also reduces the biosynthesis of cholesterol in the body. It also helps glucose get into cells which is beneficial for diabetics.

It blocks the HMG CoA Reductase Enzyme, which is what statin drugs do. It contains substances called polyphenolic flavanoids that suppress cholesterol production in much the same way that statins do, but it works in a different way that does not seem to deplete coenzyme Q10.

There are three main modes of action:

  • Blocks the HMG CoA Reductase Enzyme
  • Works on insulin receptors to improve shuttling of glucose into cells
  • Blocks cholesterol absorption in the intestine similar to plant sterols

What are some of the benefits of Citrus Bergamot?

  • It promotes fat burning and improves blood sugar control. This helps combat obesity and promotes weight loss.
  • It combats arterial stiffness due to it’s effect on sugar metabolism, and the benefits of the flavinoids it contains.
  • Can reduces LDL and triglycerides and increase HDL cholesterol
  • Helps in lowering blood pressure
  • Bergamot shows anti-tumor action and may be effective in combating neuroblastoma and other metastic cancers
  • It demonstrates anti-inflammatory and antioxidant properties that improve endothelial function

How is Bergamot taken?

When used for it’s cholesterol lowering effect, it would be taken in capsule form at appropriate doses, and this is where things get tricky. The medical profession knows a lot about drugs and the dosages that should be given, but not very much about vitamins, nutraceuticals, and herbs.

Citrus Bergamot capsulesDosage recommendations for this supplement are anecdotal and not the result of carefully controlled trials and years of clinical case studies and experience. Great care should be taken with this supplement, as it does mimic the effects of statin drugs, and thus could have some of the same side effects.

Given this fact, I think it’s wise to seek the advice of a complementary physician, who has knowledge of alternative treatments.

In research conducted at the Scripps Integrated Medicine Conference in San Diego California, in January 2012, they used 1,000 milligrams per day and got an average reduction in total cholesterol levels of 29%, a 36% reduction in LDL, and increase HDL cholesterol by 40%!

Reductions in triglycerides of 30%, and blood glucose of 20% on average were also noted. From this result the researches concluded that Citrus Bergamot extract at a dosage of 1,000 milligrams per day was an effective substitute for statin drugs for lowering LDL cholesterol, and also treating metabolic syndrome.

In Summary:

Citrus Bergamot is an interesting compound with some powerful effects on cholesterol metabolism, blood sugar control, and metabolic syndrome. It has demonstrated anti-tumor effects as well. However due to it’s statin like mode of action, I would very strongly suggest that you use it ONLY under the direction of a doctor who is knowledgeable about alternative medicine.

The doctor can help you determine if it’s right for you, and if so, how to arrive at a safe and effective dosage.

Research references:

Fitoterapia. 2011 Apr;82(3):309-16. doi: 10.1016/j.fitote.2010.10.014. Epub 2010 Nov 4.
Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies.

Fitoterapia. 2010 Sep;81(6):453-61. doi: 10.1016/j.fitote.2010.01.013. Epub 2010 Jan 20.
Neuropharmacology of the essential oil of bergamot.

Int J Cardiol. 2013 Dec 10;170(2):140-5. doi: 10.1016/j.ijcard.2013.08.125. Epub 2013 Sep 8.
Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia.

Fitoterapia. 2014 Jun;95:83-92. doi: 10.1016/j.fitote.2014.02.009. Epub 2014 Mar 2.
Effect of Citrus bergamia juice on human neuroblastoma cells in vitro and in metastatic xenograft models.

PLoS One. 2013 Apr 16;8(4):e61484. doi: 10.1371/journal.pone.0061484. Print 2013.
Mechanisms underlying the anti-tumoral effects of Citrus Bergamia juice.

Raise good cholesterol with Coenzyme Q10, and lower inflammatory LDL particles at the same time.  Sure sounds like a win-win situation for heart health, and recent research strongly supports this important role for Co Q10!

coenzyme q10 moleculeLets take a look at this new nutritional weapon against heart disease, and the other health benefits of Coenzyme Q10.

What’s Coenzyme Q10?

Coenzyme Q10 or CoQ10 as it is also referred to, was discovered by Professor Fredrick L. Crane and his research team at the University of Wisconsin–Madison Enzyme Institute in 1957.

The reduced form of CoQ10 was called ubiquinone and was identified as a powerful antioxidant and free radical scavenger, and as we will see…it also has the ability to raise good cholesterol and lower inflammatory LDL.

This fat soluble antioxidant is found in the membrane structure of the mitochondria and is a key player in the electron transport chain which functions as an energy creating mechanism in your cells. The end product of these reactions is the creation of ATP, the primary source of energy for your body.

Because of it’s vital role in cellular energy production CoQ10 is found in highest amounts in the organs and tissue that have the highest energy demands.  Your body can synthesize CoQ10 but you also need to acquire it from your diet and possibly from supplementation as well.

How Do You Get Coenzyme Q10?

You can get CoQ10 in tablet form or as a soft-gel. The softgel form is superior because it’s easier for your body to absorb. The usual dose when used to benefit the heart is from 50 to 150 milligrams. The most effective form is the “reduced” form which is called “ubiquinol.”

Food sources of CoQ10 tend to be from animal sources, such as organ meats like liver, heart, as well as muscle. Again this is because those types of organs and tissues have a high demand for energy, and CoQ10 is a vital component of energy production in both animals and humans.

Here are the top foods sources:

  • Pork heart
  • Pork liver
  • Beef heart
  • Beef liver
  • Chicken liver
  • Chicken heart
  • Sardine
  • Mackerel

If you are a vegan there ARE  vegetable sources of Coenzyme Q10, the best are whole grains, peanuts, wheat germ, broccoli, and spinach. Keep in mind though that these sources are a lot lower in CoQ10 than animal proteins, so if you are trying to make up for a deficiency in Coenzyme Q10 you may need to use a supplement like ubiquinol if you are eating a vegan diet.

Health Benefits of Coenzyme Q10

There are many health benefits of Coenzyme Q10 from protecting yourself from heart disease, to blood sugar control and better energy.  Here is a short list of medical conditions where Coenzyme Q10 can be beneficial:

  • Malignant Melanoma
  • Diabetes
  • Endothelial Dysfunction
  • Heart Disease
  • Alzheimer’s Disease
  • Senile Dementia
  • Hypertension (high blood pressure)

CoQ10 is both an antioxidant and a bio-energetic nutrient, which means it both protects cells against oxidative stress (which robs the cells of energy) and also has a vital role in making the ATP molecule that supplies energy that cells need to maintain and repair themselves.

Coenzyme Q10 and Cholesterol

CoQ10 has beneficial effects on cholesterol profiles because of it’s role as a powerful antioxidant and free radical scavenger.  It’s been established that heart disease results from inflammation and free radical damage to the heart and the arteries through which blood flows.

By fighting oxidative stress and the free radicals it produces, CoQ10 can help prevent the damage to the endothelium and the process of atherosclerosis that causes coronary artery disease. The effect of CoQ10 on cholesterol is that it will raise good cholesterol (HDL) and lower LDL.

Even though we have learned recently that cholesterol does not CAUSE heart disease, it is a FACTOR in atherosclerosis that damages arteries. Coenzyme Q10 has been shown to alter the ratio of HDL to LDL that helps protect against coronary artery disease.

Cardiologists like Dr. Stephen Sinatra have been using Coenzyme Q10 to treat heart disease for many years, and now his colleagues are beginning to embrace this nutrient and add it to their treatment protocols, because of it’s ability to raise good cholesterol and lower inflammatory LDL particles.

Coenzyme Q10 and Statins

Statins, the drugs most often given to people to lower cholesterol have some very serious side effects. Some prominent cardiologists have come out against widespread statin use because the benefits of these drugs are far outweighed by the dangers to health that these drugs pose.

Statins deplete Coenzyme Q10, leaving the body vulnerable to a number of damaging processes that are rooted in oxidative stress and free radical damage. It is for this reason that a number of cardiologists recommend that in cases where statins are used the patient MUST be given Coenzyme Q10 in supplement form to protect against this statin caused deficiency.

The Case for Co Q10

Cardiologists are starting to use it, and in fact it has been used for many years in Japan to treat heart disease. Incidentally the Japanese are the longest lived population in the world, so it seems they know a thing or two about the health benefits of Coenzyme Q10.

The ability to raise good cholesterol with Coenzyme Q10 is the real value of this nutrient in helping to treat and prevent heart disease. Given the fact that heart disease is the number one killer of Americans, Coenzyme Q10 may prove to be one of the most effective strategies to keep your cardiovascular system healthy and extend your life.

High cholesterol symptoms are not something you are going to notice. In fact they are almost non existent! The real relationship between cholesterol and heart disease kind of forced me to write this article backwards.

high cholesterol symptomsThe truth is that high cholesterol (let’s call anything beyond about 280 mg/dl high) is itself a symptom of other medical problems. You see, cholesterol is made by the body and used in all sorts of important biochemical reactions, some having to do with healing and the immune system.

Cholesterol also serves as an antioxidant as well, and your body will make more of it when you are faced with any kind of a health crisis or trauma, because it’s part of the protective and healing systems of the body.

So when cholesterol is elevated, it can be an indicator that something is wrong in the body, and that the body is attempting to heal or correct the problem.

Are there any real high cholesterol symptoms?

The answer is yes, although it’s not something that you would feel or notice on a day to day basis. It can show up during an eye examination. Your eye doctor may notice a buildup of cholesterol deposits in your eyes.

This CAN be an indicator of high cholesterol (kind of a “silent symptom”) that is itself, a symptom of other medical problems.

Arcus Senilis

There is a condition that affects the eyes called Arcus Senilis where a white or gray ring develops around the cornea of the eye.  It CAN be caused by elevated cholesterol, but not always. The rings come from cholesterol deposits but may be due to a metabolic disorder, rather than very high levels of cholesterol.

If you notice these rings, of course you should have your eyes checked, but again, this does not mean that you necessarily have a high cholesterol level. You eye doctor may recommend that you see another specialist and have the necessary tests done to determine if indeed your lipid profile (fat levels) are really elevated.

In people over 40, this condition is not all that uncommon, but really isn’t a reason for concern. In younger people it can be due to something called familial hyperlipidemia, which is a genetic condition where the person tends to have high levels of fats in their blood. In any case, if you have this condition, the best strategy is to have an eye exam and a full blood lipid screening.

The bottom line is that Arcus Senilis is a normal occurrence after 40 years of age. It’s nothing to get stressed about, but just follow up and get your blood lipids tested by your doctor. If you are a young person, it may indicate a problem with cholesterol metabolism and again should be checked out and dealt with accordingly.

High Cholesterol Symptoms That Are Silent

Again, try not to think of “high cholesterol” in and of itself as THE problem. For the most part, it’s an indicator that your body is trying to deal with another problem and the elevation in cholesterol is just it’s way of doing so. This is known in medicine as “acquired hyperlipidemia,” which means high blood fats due to some medical condition that is causing elevations in your cholesterol levels.

Your body may increase it’s cholesterol levels in response to health issues like:

  • Vitamin-D deficiency
  • Hypothyroid (sluggish thyroid function)
  • Cushings Disease (which causes chronically elevated cortisol levels)
  • Anorexia
  • Problems with your hormones and metabolism
  • Kidney disease
  • Alcoholism and alcohol toxicity
  • Diabetes and pre-diabetes

Obviously these are serious medical conditions and if you have any of these issues, your doctor should be monitoring your blood lipid profile (cholesterol and triglycerides) on a constant basis.

Drugs that Affect Cholesterol Levels

  • Estrogen and Corticosteroids (can raise HDL and Triglycerides)
  • Oral Anabolic steroids ( lower HDL)
  • Birth Control (can raise cholesterol)
  • Beta Blockers (can raise triglycerides and lower HDL)
  • Thiazide Diuretics (can raise cholesterol and triglycerides)
  • Retinoids (can increase LDL and triglycerides)

Of course if you are on any of these medications, you will have to discuss the side effects and risk to benefit ratio with your doctor. Don’t just go off medications without consulting your doctor, because this can have serious consequences.

If you are searching for an healthier or less risky alternative to drugs, that’s great, but you have to do that under the guidance of a physician who knows your medical history and can help you do so safely.

High cholesterol symptoms are a sign that there are important health issues that you and your doctor need to be dealing with. Since most people get routine lipid screenings your doctor should be aware of your lipid profile and it’s implications, but always do your own research and work with your doctor to identify problem areas and find the healthiest solutions you can for them.

Lowering triglycerides can significantly improve heart health! Your body is an totally integrated system. Knowing the cause of high triglycerides and learning how to reduce your levels will decease your risk of heart disease.

lowering triglyceridesWhile cholesterol is most often blamed for heart disease, recent scientific evidence does not support the theory that cholesterol causes cardiovascular disease. Fully half of all heart attacks occur in patients who have what are considered normal cholesterol levels. The evidence more strongly points toward triglycerides.

Triglycerides are a major factor in heart disease. An estimate two thirds of heart disease cases are at least partly a result of abnormal triglyceride levels.

There are two types of high triglycerides:

  • Familial (genetic) – usually over 400mg/dl this is not
    thought to be a cause of heart disease
  • Insulin resistant – usually 150-400mg/dl this is dangerous,
    associated with pre-diabetes and increased risk of heart disease

What are triglycerides and why are they important?

Triglycerides are lipids that are made from fats or carbohydrates you eat and are stored in the body. The higher their levels, the greater your risk for heart disease, which is why lowering triglycerides is so critical for your cardiovascular health.

Here is why elevated triglycerides are dangerous, and why lowering triglycerides is so important.

  • They are deposited in various organs including the heart
  • They can alter gene expression and increases heart disease
  • They can cause insulin resistance leading to diabetes
  • They can accumulate on artery walls causing plaque buildup
  • They thicken blood causing strokes and other circulatory
    problems
  • They contribute to abdominal obesity

What is a normal triglyceride level?

Before you go about lowering triglycerides, you need to check your levels to get a baseline so that you can tell how effective your efforts to lower them are!

The guidelines of the American Heart Association recommend that a normal triglyceride level is under 149 mg/dl.

However the Life Extension Foundation recommends an even lower level of 80-100 mg/dl measured in a fasting state.

The “fasting state” is when you have not eaten for at least 12 hours.

Unlike cholesterol, you really don’t have to worry about triglycerides going too low, so lowering triglycerides will have positive benefits for your health.  Doing the right things will bring the levels down naturally, to what is optimal for you.

Cause of high triglycerides

Just what causes these levels to become too high?

There are several factors:

  • Eating carbohydrates that raise your blood sugar rapidly
  • Problems with carbohydrate metabolism
  • Heavy drinking
  • Insulin resistance (poor insulin sensitivity)
  • A diet that consists of over 60% carbohydrate
  • Smoking
  • Lack of exercise – low physical activity
  • Obesity
  • Metabolic Syndrome
  • Kidney disease
  • Certain prescription medications (estrogen, birth control pills, tamoxifen, steroids, beta-blockers, and diuretics)

Lowering triglycerides

Lowering triglycerides really comes down to two things, restricting sugars, and getting regular exercise. Of course there is more to it than that, but those are the two most effective things.

Most people eat too many refined carbohydrates, and that is the cause of high triglycerides.

A “low glycemic diet” high in fiber will help in lowering triglycerides. This is because fiber slows down the entry of sugars into the bloodstream. Rapid entry of sugar into the bloodstream causes insulin to rise, and this promotes inflammation which in turn causes triglyceride levels to go up!

Nutritional supplements such as circumin, and green coffee extract, can also help by lowering inflammation, and helping the body manage blood sugar levels more efficiently.

Exercise also helps in lowering triglycerides  because it increases insulin sensitivity, maintains lean muscle, and mobilizes fatty acids to be burned for energy.

Below are some short simple steps for lowering triglycerides:

  • Limit your carbohydrates to mostly fresh vegetables – go easy on fruits
  • Eat what is known as a low glycemic diet
  • Avoid over consuming grains, and eating sweets
  • Eat lean proteins
  • Use nutritional supplements as you need them
  • Get some kind of brisk exercise each day

That’s pretty much it! Lowering triglycerides willboost heart health and improve the health of your entire cardiovascular system.  It’s probably the best things you can do to put yourself on a path to better health!

The VAP cholesterol test is the very latest diagnostic test to determine your risk of heart disease. Standard cholesterol level tests identify only 40% of those at risk for heart disease. In fact, half of all heart attacks are suffered by people with normal levels!

VAP cholesterol testProblems With Traditional Tests

One of the shortcomings of standard tests was that they didn’t measure or identify lipoprotein particles associated with increased inflammation.

Medical science has really caught on to the fact that it’s really the damage that inflammation does to your arteries that causes heart disease.

The old standard for testing was to measure LDL, HDL, and total cholesterol and to use the ratio between LDL and HDL to determine a person’s risk of heart disease. This was fairly accurate for it’s time, but it has been superseded by a new standard for determining your risk.

The old testing protocol produced four measurements:

  • Total cholesterol
  • Triglycerides
  • LDL – Low-density lipoprotein
  • HDL – High-density lipoprotein

Although these four elements do have some value in determining your risk of heart attack, they lack the accuracy of newer test methods in determining risk.

Enter the VAP Cholesterol Test

Medical science has recently developed a newer and more accurate test for heart disease risk called VAP  for (Vertical Auto Profile). This test benefits you in two ways.

  • It is THE most accurate indicator of your risk of heart attack
  • It helps identify various risk factors that you can control to prevent a heart attack

VAP cholesterol test can pinpoint your risk, taking much of the guesswork out of this medical diagnosis. This is very helpful for people who have test results that show normal levels, but who’s true heart attack risk can now be successfully identified.

Not all doctors provide the VAP cholesterol test, but it’s use is increasing as more and more doctors realize their standard testing fails to identify everyone that is at risk.

The VAP test is done the same way as other tests where a nurse or lab technician draws your blood and then sends it to a laboratory which then runs the test and returns the test results to your doctor.

How Does The Test Work?

The test identifies the following:

  • Identifies small dense LDL particles that cause arterial plaque
  • HDL2 and HDL3
  • IDL – Intermediate-density lipoprotein
  • Lipoprotein A
  • (VLDL1, VLDL2, VLDL3) Very low density lipoproteins

These small sub-fractions of cholesterol pose the greatest danger to you. The VAP cholesterol test will identify these particles, their density, and distribution. This information helps your doctor create a customized approach to reducing your risk of a heart attack and strokes.

Standard test results are still valuable as a screening method for heart disease. It is an inexpensive way of determining if you are at increased risk. The addition of the VAP test further clarifies your degree of risk and allows you to make needed lifestyle changes to head off a possible heart attack.

The key is to identify risks early while there is still time to reverse them with diet and exercise rather than drugs such as statins which have toxic side effects. The test really represents an advance in thinking that more accurately gauges how these individual lipoprotein particles affect your overall risk for heart disease.

The VAP cholesterol test will soon become the standard for determining your heart attack risk. This will go a long way toward making heart attacks increasingly rare and survivable! Ask YOUR doctor about the VAP test, and start reducing your risk now!